Evidence-based peptide reference · updated April 2026
The clinical source of truth for peptide therapy.
48 peptides, 520 clinics, live FDA tracking, and community signal — synthesized for patients, clinicians, and researchers. Medical-reviewer signed.
Reviewed by Marko Maal, MSc PharmacyUpdated May 17, 202646 articles · 4 cornerstonesEvidence-tier labeled
Direct answers
Is compounded semaglutide still legal in May 2026?
It depends on the pharmacy type. The May 4, 2026 FDA proposal excludes semaglutide and tirzepatide from the 503B bulks list — large compounding outsourcers can no longer mass-produce them. 503A patient-specific compounding remains legal under documented medical necessity (e.g., allergy to a Wegovy filler, unmet clinical need). Brand-name Wegovy and Zepbound are unaffected.
Read the full 503B explainerWhat peptides are, what they aren't, and how they actually work.
The complete, medical-reviewer-signed beginner's guide. Mechanism, evidence tiers, dosing, legal status, and how to separate real therapeutics from biohacker hype.
Short chains of 2–50 amino acids that act as biological signaling molecules. They tell cells what to do — release growth hormone, migrate to damaged tissue, modulate hunger. Some are FDA-approved (semaglutide, tirzepatide). Some are compounded (BPC-157). Some are research-only (KPV, MOTS-c).
Covers: 48 peptides · 22 conditions · all 50 states
Start with a goal
8 pillars · goal-based navigation
Most searched peptides
All peptides →Ranked by 30-day query volume across Google + LLM citations
Retatrutide
+38%Metabolic
- inject
525K/moResearch onlyOrforglipron
+92%Metabolic
- pill
375K/moResearch onlySemaglutide
+8%Metabolic
- pill
- inject
201K/moFDA approvedCagriSema
+55%Metabolic
- inject
140K/moResearch onlyTirzepatide
+61%Metabolic
- inject
- pill
98.4K/moFDA approvedArgireline
+11%Skin / anti-aging
- topical
85K/moCosmeticTesamorelin
+14%Growth hormone
- inject
75K/moFDA approvedCerebrolysin
+27%Cognitive
- inject
- nasal
62K/moResearch onlyTB-500
+22%Recovery
- inject
58K/moCat 2 → review
Find a clinic
Telehealth · all 50 states
Telehealth coverage across all 50 states + 20+ verified providers
Comparison pages
All comparisons →Side-by-side mechanism, dosing, evidence
Community signal · live
Open full feed →Synthesized across Reddit, Bluesky, PubMed, and FDA — refreshed on cron, latest first.
Items / 24h
0
live
Reddit posts
295
tracked
Research
27
PubMed papers
FDA alerts
0
this period
- ⬤ REDDITr/Retatrutide1h ago
Unpopular Opinion about Reta starting dose when transitioning from 15 mg Tirzepatide
Mentions Retatrutide
- ⬤ REDDITr/Retatrutide1h ago
Eli Lilly says next-generation weight loss drug clears crucial obesity trial
Mentions Retatrutide
- ⬤ REDDITr/Semaglutide1h ago
5 days on Foundayo
Mentions Semaglutide
- ⬤ REDDITr/Semaglutide2h ago
1 week with Semaglutide.
Mentions Semaglutide
- ⬤ REDDITr/Retatrutide3h ago
Retatrutide TRIUMPH Phase 3 Top Line results MEGATHREAD
Mentions Retatrutide
- ⬤ REDDITr/Retatrutide4h ago
Lates NY Times Article on Reta
Mentions Retatrutide
What's published
Live counts · auto-updated
Peptides covered
27
Clinics tracked
20
Supporting articles
46
Comparison pages
12
Goal pillars
8
Legal guides
0
Evidence tiers
Every claim is tagged Tier 1–5 — RCT to anecdotal — so you can read intensity and confidence at a glance. No hype.
Protocol logs
Structured submissions, not freeform forum chatter. Dose × duration × delivery × result. Aggregations are reviewed before they're surfaced.
Lab transparency
Vendor products go to ISO-17025 labs. Results published whether or not the vendor likes the outcome.